Smart gauze to combat antibiotic-resistant wound infections
Researchers at the University of Washington previously discovered that as amyloid fibrils form within biofilms, they pass through an intermediate stage called an alpha-sheet (a-sheet) peptide structure, which plays a key role in making infections more difficult to treat.
In a recent study, the research team used computational design to create synthetic peptides that mimic a-sheets and can block amyloid fibril formation.
For the full story, see the April 2025 edition of Medical Textiles.
Image: Daggett Lab/University of Washington